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Investlytic score: 1/5 criteria met. Data as of 01/11/2026.
- ❌ Price trend failed
- ❌ Growth failed
- ✅ Debt passed
- ❌ P/E failed
- ❌ Correction failed
Price trend
Overall trend (8 years): insufficient progression (less than x1.5).
Price change 2018 → 2019: -15.68%
Price change 2019 → 2020: 380.83%
Price change 2020 → 2021: -46.75%
Price change 2021 → 2022: -37.65%
Price change 2022 → 2023: -22.83%
Price change 2023 → 2024: -5.03%
Price change 2024 → 2025: -18.99%
Price change 2025 → 2026: 13.45%
Price change 2026 (year to date): 15.12%
Financial growth
Revenue CAGR (8 years): -100.00%
Earnings CAGR (8 years): N/A
Growth status: insufficient data or negative trend.
Debt
Debt-to-equity ratio: 0.04
Debt/equity < 0.5 (maximum threshold).
P/E (Price/Earnings)
P/E ratio: -6.51
P/E > 25.0 (maximum threshold).
Correction (6 months)
Current correction: 31.17% from the high over 6 months.
Excessive correction (> 20.0%).
Criteria of the Investlytic model
- / 5Free with the Investlytic logo. Paste this line into your page: options.
<script src="https://investlytic.co/encart.js" data-symbole="DNLI" data-lang="en"></script>Price trend
Price & trend
Interactive chart →💰 Dividend
Dividend ranking →⚖️ Comparison with the market
All stocks →| Stock | P/E | Dette/FP | Revenue growth | Rating |
|---|---|---|---|---|
| Denali Therapeutics Inc. | – | 0.04 | – | 🔒 |
| Virbac S.A. | 19.3 | 0.26 | +6.5 % | ★ 4/5 |
| Addus HomeCare Corporation | 18.8 | 0.19 | +11.7 % | ★ 4/5 |
| Fleury S.A. | 16.6 | 1.05 | +16.2 % | – |
| Option Care Health, Inc. | 18.5 | 0.96 | +18.7 % | – |
Data from the Investlytic screener. The rating of the stock being viewed is reserved for members.
Detailed analysis · Price trend
-
Revenues & profits
Revenue and net income
Financial indicators
Annual financial statements
| Fiscal year | Revenue | Net income | Net margin | EPS | Revenue growth |
|---|
Key reported figures
Revenue, net income and net margin reported by Denali Therapeutics Inc. over the latest fiscal years.
| Fiscal year | Revenue | Net income | Net margin | Revenue growth |
|---|---|---|---|---|
| 2018 | 129 m | -36.2 m | -28.1 % | n/a |
| 2019 | 26.7 m | -198 m | -740.7 % | -79.3 % |
| 2020 | 336 m | 71.1 m | 21.2 % | +1,158.2 % |
| 2021 | 48.7 m | -291 m | -597.1 % | -85.5 % |
| 2022 | 108 m | -326 m | -300.6 % | +122.9 % |
| 2023 | 331 m | -145 m | -43.9 % | +204.7 % |
Amounts converted to USD. Source: published annual accounts, collected on 06/11/2026.
Accounts and financial health
Balance sheet and cash flow published by Denali Therapeutics Inc. over the last fiscal years, strength scores and valuation by discounted cash flow (DCF).
| Fiscal year | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|
| Cash and investments | 865 m | 1.3 bn | 1.0 bn | 832 m | 868 m |
| Total Debt | 64.0 m | 60.4 m | 52.2 m | 48.7 m | 36.8 m |
| Net Debt | -229 m | -158 m | -74.9 m | -126 m | -169 m |
| Equity | 962 m | 1.0 bn | 1.0 bn | 1.2 bn | 1.0 bn |
| Total assets | 1.4 bn | 1.5 bn | 1.2 bn | 1.4 bn | 1.1 bn |
| Operating cash flow | -211 m | -245 m | -358 m | -348 m | -413 m |
| Investments (capex) | 8.5 m | 17.8 m | 12.9 m | 15.9 m | 9.5 m |
| Free cash-flow | -220 m | -263 m | -371 m | -364 m | -422 m |
| Share buybacks | 0 | 0 | 0 | 0 | 0 |
| Dividends paid | 0 | 0 | 0 | 0 | 0 |
Amounts in USD, currency of the published accounts.
Trailing 12-month ratios
Altman Z: default risk estimated from the balance sheet and earnings. Piotroski: 9 tests on profitability, debt and efficiency. DCF: estimated value from discounted future cash flows, a model and not a forecast. Source: annual accounts published by the company, data as of 09/11/2026.
Analyst consensus and forecasts
What the financial analysts covering Denali Therapeutics Inc. publish: ratings, price targets and earnings forecasts.
Breakdown of ratings
Price targets: published for companies listed in the United States only.
Track record against expectations: reported EPS above consensus 7 times over the last 12 releases.
Source: ratings and forecasts published by analysts, collected on 07/11/2026. An analyst rating or target is not a guarantee.
Who owns the stock
Free float, institutional investors, large funds, executives and elected officials: declared positions in Denali Therapeutics Inc.
Large funds tracked
| Fund | Shares | Value (USD) | Weight in the fund | Change | Quarter |
|---|---|---|---|---|---|
| State Street | 14.1 m | 363 m | 0.0 % | +124.8 % | 2026Q2 |
| BlackRock | 14.0 m | 361 m | 0.0 % | +7.6 % | 2026Q2 |
| Baillie Gifford | 12.0 m | 308 m | 0.3 % | -0.9 % | 2026Q2 |
| Vanguard Group | 13.1 m | 216 m | 0.0 % | +8.9 % | 2025Q4 |
| Fidelity | 4.5 m | 117 m | 0.0 % | -0.9 % | 2026Q2 |
| Goldman Sachs | 4.2 m | 107 m | 0.0 % | -5.7 % | 2026Q2 |
| Geode Capital Management | 4.0 m | 102 m | 0.0 % | +6.6 % | 2026Q2 |
| T. Rowe Price | 3.1 m | 80.7 m | 0.0 % | +27.3 % | 2026Q2 |
Latest insider transactions
| Date | Person | Side | Amount |
|---|---|---|---|
| 04/09/2026 | Chin Peter Scott | sale | 36,868 USD |
| 02/09/2026 | Thornberry Nancy | sale | 247,328 USD |
| 02/09/2026 | Thornberry Nancy | sale | 14,600 USD |
| 01/09/2026 | Schuth Alexander O. | sale | 64,882 USD |
| 11/08/2026 | Schuth Alexander O. | sale | 71,625 USD |
Sources: 13F filings (quarter shown), executives' Form 4 filings and US Congress members' disclosures, collected on 08/11/2026. Detailed disclosure obligations mainly apply to companies listed in the United States.
PEA and practical information
Rule applied: the French PEA accepts shares of companies headquartered in the European Union or the European Economic Area and subject to corporate income tax; ADRs and tax-exempt property companies (SIIC) are excluded. The institution holding the PEA confirms eligibility.
Frequently asked questions about Denali Therapeutics Inc.
What is the Denali Therapeutics Inc. share price?
Latest recorded price: 20.07 USD on 06/11/2026, for a market cap of 3.2 bn USD.
What is the revenue of Denali Therapeutics Inc.?
331 m USD for fiscal year 2023, with net income of -145 m USD (net margin -43.9 %).
What do analysts say about Denali Therapeutics Inc.?
Out of 19 analysts: 19 buy or strong buy, 0 hold, 0 sell or strong sell.
Is Denali Therapeutics Inc. stock eligible for the French PEA?
No: the company is headquartered outside the European Union and the European Economic Area (ISIN US24823R1059).
How many employees does Denali Therapeutics Inc. have?
443 full-time employees according to the latest published profile.
Who runs Denali Therapeutics Inc.?
Ryan J. Watts is the company's chief executive.
Which large funds own Denali Therapeutics Inc.?
As of 2026Q2, among the large funds tracked: State Street, BlackRock, Baillie Gifford, Vanguard Group, Fidelity.