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Stock Krystal Biotech, Inc. KRYS

Krystal Biotech, Inc. — Investlytic score 3/5 on the five criteria.

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60/ 100
Score Investlytic · 5 criteria

Analysis in progress…

Investlytic score: 3/5 criteria met.

  • ✅ Price trend passed
  • ⚠️ Mixed growth
  • ✅ Debt passed
  • ❌ P/E failed
  • ✅ Correction passed

Price trend

Overall trend (8 years): the price has been multiplied by at least 1.5.

Price change 2018 → 2019: 166.51%

Price change 2019 → 2020: 8.34%

Price change 2020 → 2021: 16.58%

Price change 2021 → 2022: 13.25%

Price change 2022 → 2023: 56.60%

Price change 2023 → 2024: 26.28%

Price change 2024 → 2025: 57.37%

Price change 2025 → 2026: 31.95%

Price change 2026 (year to date): 31.75%

Financial growth

Revenue CAGR (8 years): 133.54%

Earnings CAGR (8 years): N/A

Growth status: positive trend (>1%/yr) in revenue, earnings data insufficient/N/A.

Debt

Debt-to-equity ratio: 0.01

Debt/equity < 0.5 (maximum threshold).

P/E (Price/Earnings)

P/E ratio: 40.39

P/E > 25.0 (maximum threshold).

Correction (6 months)

Current correction: 13.97% from the high over 6 months.

Correction between 10.0% and 20.0% (target range).

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Criteria of the Investlytic model

- / 5
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Score out of 100, model verdict (buy, watch, sell) and details of the 5 criteria · visible with a free account.

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Price trend

Price & trend

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⚖️ Comparison with the market

All stocks →
StockP/EDette/FPRevenue growthRating
Krystal Biotech, Inc.41.60.01–🔒
Bio-Rad Laboratories, Inc.40.10.20+2.0 %–
bioMérieux S.A.22.80.11+7.6 %★ 4/5
Oscar Health, Inc.21.70.44+66.3 %–
Ipsen S.A.25.40.20+7.9 %★ 4/5

Data from the Investlytic screener. The rating of the stock being viewed is reserved for members.

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Detailed analysis · Price trend

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Global model trend and annual price variations · visible with a free account.

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Revenues & profits

Revenue and net income

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Chart of revenues and net income over 8 periods · real data, no estimates.

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Financial indicators

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18 financial indicators analyzed by groups of criteria: valuation, profitability, growth, solidity, dividend, and momentum.

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Annual financial statements

Fiscal yearRevenueNet income Net marginEPSRevenue growth
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Complete annual financial statements: revenue, net income, margin, and EPS over 8 fiscal years.

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Key reported figures

Revenue, net income and net margin reported by Krystal Biotech, Inc. over the latest fiscal years.

Revenue
389 m USD
fiscal year 2025
Net income
205 m USD
fiscal year 2025
Net margin
52.6 %
fiscal year 2025
Market cap
8.9 bn USD
Fiscal yearRevenueNet incomeNet marginRevenue growth
20181.0 m-10.9 m-1,060.3 %n/a
202350.7 m10.9 m21.6 %+4,836.6 %
2024291 m89.2 m30.7 %+473.0 %
2025389 m205 m52.6 %+33.9 %

Amounts converted to USD. Source: published annual accounts, collected on 06/11/2026.

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Accounts and financial health

Balance sheet and cash flow published by Krystal Biotech, Inc. over the last fiscal years, strength scores and valuation by discounted cash flow (DCF).

Overview
solid accounts
according to Altman Z, Piotroski and net debt
Altman Z-score
37.49
safe zone (above 2.99)
Piotroski Score
4 / 9
4 to 6: average accounts
DCF Value
517.79 USD
DCF above share price · share price 303.86 USD, gap +70.4 %
Net Debt / EBITDA
-1.80 x
net cash
Fiscal year20212022202320242025
Cash and investments438 m379 m532 m598 m828 m
Total Debt8.0 m8.9 m8.1 m7.3 m9.3 m
Net Debt-333 m-153 m-350 m-338 m-487 m
Equity594 m522 m779 m946 m1.2 bn
Total assets626 m558 m818 m1.1 bn1.3 bn
Operating cash flow-47.9 m-101 m-88.8 m123 m201 m
Investments (capex)68.3 m53.0 m11.8 m4.2 m12.0 m
Free cash-flow-116 m-154 m-101 m119 m189 m
Share buybacks00000
Dividends paid00000

Amounts in USD, currency of the published accounts.

Trailing 12-month ratios

Price / earnings (P/E)39.28 x
Price / book value6.21 x
Return on Equity (ROE)17.0 %
Return on Invested Capital (ROIC)13.7 %
Net margin47.9 %
Debt / equity0.01 x
Current ratio7.89 x
Free cash-flow yield3.5 %

Altman Z: default risk estimated from the balance sheet and earnings. Piotroski: 9 tests on profitability, debt and efficiency. DCF: estimated value from discounted future cash flows, a model and not a forecast. Source: annual accounts published by the company, data as of 09/11/2026.

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Valuation and competitors

Krystal Biotech, Inc. compared with its sector on the same exchange and with its main competitors.

Company P/E
37.7
83.6 % above the sector
Sector median P/E
20.5
healthcare, Nasdaq
Sector over 10 years
26.5
10-year median, range 16.9 to 46.3

Direct competitors

CompanyMarket cap (USD)P/ENet margin
Krystal Biotech, Inc.9.8 bn41.652.6 %
MeiraGTx Holdings plc MGTX911 mn/a-140.3 %
Abeona Therapeutics Inc. ABEO249 mn/a1,223.1 %
REGENXBIO Inc. RGNX475 mn/a-113.8 %
Rocket Pharmaceuticals, Inc. RCKT268 mn/a0.0 %
Sana Biotechnology, Inc. SANA769 mn/a0.0 %
Sector median (Nasdaq)20.5

Trailing 12-month P/E. Sector: median of companies in the same sector listed on the same exchange, collected on . Competitors: comparable companies named by the data provider.

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Analyst consensus and forecasts

What the financial analysts covering Krystal Biotech, Inc. publish: ratings, price targets and earnings forecasts.

Majority rating
buy
17 analysts

Breakdown of ratings

strong buy 0buy 17hold 0sell 0strong sell 0

Price targets: published for companies listed in the United States only.

Track record against expectations: reported EPS above consensus 10 times over the last 12 releases.

Source: ratings and forecasts published by analysts, collected on 07/11/2026. An analyst rating or target is not a guarantee.

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Who owns the stock

Free float, institutional investors, large funds, executives and elected officials: declared positions in Krystal Biotech, Inc.

Free float
79.8 %
share of freely traded shares
Large funds tracked
22
hold the stock as of 2026Q2
Executives (insiders)
0 / 33
0 purchases, 33 sales in 130 days

Large funds tracked

FundSharesValue (USD)Weight in the fundChangeQuarter
Fidelity4.4 m1.6 bn0.1 %+1.0 %2026Q2
BlackRock4.2 m1.6 bn0.0 %+6.1 %2026Q2
State Street2.7 m1.0 bn0.0 %+105.6 %2026Q2
Vanguard Group2.8 m685 m0.0 %-0.5 %2025Q4
Capital World Investors777,843289 m0.0 %-5.7 %2026Q2
Geode Capital Management698,993260 m0.0 %+8.5 %2026Q2
T. Rowe Price687,400255 m0.0 %+41.7 %2026Q2
Invesco324,755121 m0.0 %+29.2 %2026Q2

Latest insider transactions

DatePersonSideAmount
04/09/2026Krishnan Sumasale184,361 USD
04/09/2026Krishnan Sumasale713,277 USD
04/09/2026Krishnan Sumasale1.2 m USD
04/09/2026Krishnan Sumasale1.4 m USD
04/09/2026Krishnan Sumasale1.1 m USD
04/09/2026Krishnan Sumasale1.2 m USD

Sources: 13F filings (quarter shown), executives' Form 4 filings and US Congress members' disclosures, collected on 08/11/2026. Detailed disclosure obligations mainly apply to companies listed in the United States.

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PEA and practical information

PEA eligibility
no
head office outside the EU and EEA
Listing exchange
Nasdaq
IPO: 20/09/2017
ISIN code
US5011471027
Workforce
275
full-time employees
Chief executive
Krish S. Krishnan

Rule applied: the French PEA accepts shares of companies headquartered in the European Union or the European Economic Area and subject to corporate income tax; ADRs and tax-exempt property companies (SIIC) are excluded. The institution holding the PEA confirms eligibility.

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Frequently asked questions about Krystal Biotech, Inc.

What is the Krystal Biotech, Inc. share price?

Latest recorded price: 300.88 USD on 06/11/2026, for a market cap of 8.9 bn USD.

What is the revenue of Krystal Biotech, Inc.?

389 m USD for fiscal year 2025, with net income of 205 m USD (net margin 52.6 %).

What do analysts say about Krystal Biotech, Inc.?

Out of 17 analysts: 17 buy or strong buy, 0 hold, 0 sell or strong sell.

What is the P/E ratio of Krystal Biotech, Inc.?

Trailing 12-month P/E of 37.7, against 20.5 for the sector median on the same exchange (10-year median: 26.5).

Is Krystal Biotech, Inc. stock eligible for the French PEA?

No: the company is headquartered outside the European Union and the European Economic Area (ISIN US5011471027).

How many employees does Krystal Biotech, Inc. have?

275 full-time employees according to the latest published profile.

Who runs Krystal Biotech, Inc.?

Krish S. Krishnan is the company's chief executive.

Which large funds own Krystal Biotech, Inc.?

As of 2026Q2, among the large funds tracked: Fidelity, BlackRock, State Street, Vanguard Group, Capital World Investors.

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