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Stock Axsome Therapeutics, Inc. AXSM

Axsome Therapeutics, Inc. — Investlytic score 1/5 on the five criteria.

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20/ 100
Score Investlytic · 5 criteria

Analysis in progress…

Investlytic score: 1/5 criteria met. Data as of 01/11/2026.

  • ✅ Price trend passed
  • ❌ Growth failed
  • ❌ Debt failed
  • ❌ P/E failed
  • ❌ Correction failed

Price trend

Overall trend (8 years): the price has been multiplied by at least 1.5.

Price change 2018 → 2019: 3565.25%

Price change 2019 → 2020: -21.18%

Price change 2020 → 2021: -53.63%

Price change 2021 → 2022: 104.16%

Price change 2022 → 2023: 3.19%

Price change 2023 → 2024: 6.31%

Price change 2024 → 2025: 115.86%

Price change 2025 → 2026: -20.92%

Price change 2026 (year to date): -19.17%

Financial growth

Revenue CAGR (8 years): N/A

Earnings CAGR (8 years): N/A

Growth status: insufficient data or negative trend.

Debt

Debt-to-equity ratio: 2.73

Debt/equity > 0.5 (maximum threshold).

P/E (Price/Earnings)

P/E ratio: -37.71

P/E > 25.0 (maximum threshold).

Correction (6 months)

Current correction: 43.40% from the high over 6 months.

Excessive correction (> 20.0%).

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Criteria of the Investlytic model

- / 5
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Investlytic rating reserved for members

Score out of 100, model verdict (buy, watch, sell) and details of the 5 criteria · visible with a free account.

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Price trend

Price & trend

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⚖️ Comparison with the market

All stocks →
StockP/EDette/FPRevenue growthRating
Axsome Therapeutics, Inc.–2.73–🔒
Ionis Pharmaceuticals, Inc.–5.34+15.5 %–
Oscar Health, Inc.21.90.44+66.3 %–
Hims & Hers Health, Inc.–2.07+74.7 %–
Krystal Biotech, Inc.37.70.01––

Data from the Investlytic screener. The rating of the stock being viewed is reserved for members.

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Detailed analysis · Price trend

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Global model trend and annual price variations · visible with a free account.

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Revenues & profits

Revenue and net income

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Chart of revenues and net income over 8 periods · real data, no estimates.

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Financial indicators

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18 financial indicators analyzed by groups of criteria: valuation, profitability, growth, solidity, dividend, and momentum.

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Annual financial statements

Fiscal yearRevenueNet income Net marginEPSRevenue growth
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Complete annual financial statements: revenue, net income, margin, and EPS over 8 fiscal years.

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Key reported figures

Revenue, net income and net margin reported by Axsome Therapeutics, Inc. over the latest fiscal years.

Revenue
638 m USD
fiscal year 2025
Net income
-183 m USD
fiscal year 2025
Net margin
-28.7 %
fiscal year 2025
Market cap
7.0 bn USD
Fiscal yearRevenueNet incomeNet marginRevenue growth
202250.0 m-187 m-374.0 %n/a
2023271 m-239 m-88.4 %+440.8 %
2024386 m-287 m-74.5 %+42.5 %
2025638 m-183 m-28.7 %+65.5 %

Amounts converted to USD. Source: published annual accounts, collected on 06/11/2026.

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Accounts and financial health

Balance sheet and cash flow published by Axsome Therapeutics, Inc. over the last fiscal years, strength scores and valuation by discounted cash flow (DCF).

Overview
average accounts
according to Altman Z, Piotroski and net debt
Altman Z-score
4.12
safe zone (above 2.99)
Piotroski Score
3 / 9
0 to 3: fragile accounts
Net Debt / EBITDA
0.66 x
low debt
Fiscal year20212022202320242025
Cash and investments86.5 m201 m386 m315 m323 m
Total Debt49.7 m94.7 m186 m193 m241 m
Net Debt-36.8 m-106 m-200 m-122 m-81.6 m
Equity15.6 m110 m191 m57.0 m88.3 m
Total assets87.8 m331 m588 m568 m690 m
Operating cash flow-108 m-117 m-145 m-128 m-93.4 m
Investments (capex)308,000702,000582,000270,000480,000
Free cash-flow-109 m-117 m-146 m-129 m-93.9 m
Share buybacks00000
Dividends paid00000

Amounts in USD, currency of the published accounts.

Trailing 12-month ratios

Price / earnings (P/E)-43.26 x
Price / book value65.84 x
Return on Equity (ROE)-189.7 %
Return on Invested Capital (ROIC)-39.6 %
Net margin-18.2 %
Debt / equity2.07 x
Current ratio1.42 x
Interest coverage-27.32 x
Free cash-flow yield-1.2 %

Altman Z: default risk estimated from the balance sheet and earnings. Piotroski: 9 tests on profitability, debt and efficiency. DCF: estimated value from discounted future cash flows, a model and not a forecast. Source: annual accounts published by the company, data as of 09/11/2026.

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Analyst consensus and forecasts

What the financial analysts covering Axsome Therapeutics, Inc. publish: ratings, price targets and earnings forecasts.

Majority rating
buy
27 analysts
Average price target
272.27 USD
from n/a to n/a, 55 targets over 12 months
Gap with the share price
+88.5 %
price 144.43 USD on 30/10/2026

Breakdown of ratings

strong buy 0buy 26hold 1sell 0strong sell 0

Average target over the last 3 months: 272.27 USD (11 targets).

Track record against expectations: reported EPS above consensus 4 times over the last 12 releases.

Source: ratings and forecasts published by analysts, collected on 07/11/2026. An analyst rating or target is not a guarantee.

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Who owns the stock

Free float, institutional investors, large funds, executives and elected officials: declared positions in Axsome Therapeutics, Inc.

Large funds tracked
26
hold the stock as of 2026Q2
Executives (insiders)
0 / 3
0 purchases, 3 sales in 130 days

Large funds tracked

FundSharesValue (USD)Weight in the fundChangeQuarter
Vanguard Group4.2 m761 m0.0 %-0.4 %2025Q4
BlackRock3.1 m760 m0.0 %-20.7 %2026Q2
Invesco1.7 m409 m0.0 %+28.8 %2026Q2
State Street1.6 m385 m0.0 %+59.2 %2026Q2
Fidelity1.5 m377 m0.0 %-1.8 %2026Q2
Geode Capital Management967,172237 m0.0 %-16.8 %2026Q2
Morgan Stanley804,082197 m0.0 %+68.7 %2026Q2
Two Sigma Investments669,478164 m0.1 %+107.4 %2026Q2

Latest insider transactions

DatePersonSideAmount
03/09/2026Jacobson Mark L.sale2.1 m USD
06/08/2026Tabuteau Herriotsale997,007 USD
05/08/2026Tabuteau Herriotsale9.5 m USD

Sources: 13F filings (quarter shown), executives' Form 4 filings and US Congress members' disclosures, collected on 08/11/2026. Detailed disclosure obligations mainly apply to companies listed in the United States.

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PEA and practical information

PEA eligibility
no
head office outside the EU and EEA
Listing exchange
Nasdaq
IPO: 19/11/2015
ISIN code
US05464T1043
Workforce
712
full-time employees
Chief executive
Herriot Tabuteau

Rule applied: the French PEA accepts shares of companies headquartered in the European Union or the European Economic Area and subject to corporate income tax; ADRs and tax-exempt property companies (SIIC) are excluded. The institution holding the PEA confirms eligibility.

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Frequently asked questions about Axsome Therapeutics, Inc.

What is the Axsome Therapeutics, Inc. share price?

Latest recorded price: 132.37 USD on 06/11/2026, for a market cap of 7.0 bn USD.

What is the revenue of Axsome Therapeutics, Inc.?

638 m USD for fiscal year 2025, with net income of -183 m USD (net margin -28.7 %).

What do analysts say about Axsome Therapeutics, Inc.?

Out of 27 analysts: 26 buy or strong buy, 1 hold, 0 sell or strong sell. Average price target: 272.27 USD, i.e. +88.5 % from the share price.

Is Axsome Therapeutics, Inc. stock eligible for the French PEA?

No: the company is headquartered outside the European Union and the European Economic Area (ISIN US05464T1043).

How many employees does Axsome Therapeutics, Inc. have?

712 full-time employees according to the latest published profile.

Who runs Axsome Therapeutics, Inc.?

Herriot Tabuteau is the company's chief executive.

Which large funds own Axsome Therapeutics, Inc.?

As of 2026Q2, among the large funds tracked: Vanguard Group, BlackRock, Invesco, State Street, Fidelity.

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